Ending HIV: The Kick and Kill approach may prove a breakthough to cure
HIV researchers and scientists are hailing a new treatment study by Danish researcher Ole Schmeltz Søgaard, of Aahus University as a breakthrough in the search for a cure for HIV.
Speaking at a press conference, Schmeltz Søgaard revealed his recent study which trialled the use of a new group of drugs, histone deacetylase (HDAC) inhibitors.
Traditionally used to treat leukaemia, the drugs had been shown to reactivate HIV from latency on a systemic level, and Schmeltlz has been working on a study with six patients to see if the inhibitors have the same response in patients.
The approach, which was likened by Australian Professor Lewin of the Burnett Institute as a “kick and kill approach” as it kicks the virus out and makes it visible and thus able to respond to standard treatment bodes well for helping to unmask the HIV cells that don't respond to standard treatment.
Schmeltz Søgaard’s findings have been hailed as a major step towards finding a cure.
Currrently T-Cells cant find HIV cells that are latent or hiding in CD4 cells so they can not kill the virus. When A person takes Anti Retro Viral (ART) therapy it keeps the virus in check – sometimes even at undetectable levels but as we have now discovered from the Mississippi baby case HIV can remain latent in cells for years before reactivating.
Schemltz Sogaard’s findings exposes the hidden reservoir of HIV and kicks it out into the blood stream – making it detectable once more.